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Search Results for " candida albicans "

20

Compounds

Cat No. Product Name Synonyms Targets
T1388 Fluconazole UK-49858 Antibiotic , Antifection , Antifungal
Fluconazole (UK-49858) is a triazole antifungal agent that is used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS.
T38240 2,6-Dichlorodiphenylamine Antibacterial
2,6-Dichlorodiphenylamine is an analogue of Diclofenac Sodium and has anti-Candida albicans activity. Diclofenac Sodium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1...
T27617 Inz-1 P450
Inz-1 is an effective and fungal-selective inhibitor of mitochondrial cytochrome bc1 with IC50s of 8.092 and 45.320 μM for yeast and human. Inz-1 reverses Fluconazole or other triazole antifungals’ resistance in the path...
T21678 3MB-PP1 PLK
3MB-PP1 is a bulky purine analog and a Polo-like kinase 1 (Plk1) inhibitor. In cells expressing analog-sensitive Plk1 alleles, 3MB-PP1 blocks mitotic progression and cell division arise by targeting Plk1. 3MB-PP1 specifi...
T19717 Cyclo-L-Trp-L-Trp Antifungal
Cyclo-L-Trp-L-Trp is a broad-spectrum antifungal. It also induces a high degree of acetylation of histones.
T14046 Anandamide (5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide Cannabinoid Receptor , Endogenous Metabolite
Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55) in the central nervous sy...
T17022 Tebuconazole P450 , Antifungal
Tebuconazole is an agricultural azole fungicide. It can also inhibit CYP51 (IC50s: 0.9 and 1.3 μM for Candida albicans CYP51 and truncated Homo sapiens CYP51, respectively).
T9602 Monocaprin Anti-infection , Antibacterial
Monocaprin is a 1-monoglyceride of capric acid that has antimicrobial activity against enveloped viruses, certain bacteria, and the yeast Candida albicans.
T7029 Pseudolaric Acid C Antifungal
Pseudolaric Acid C has weak antifungal activity against Candida albicans.
T16412 Oteseconazole VT-1161 P450 , Antifungal
Oteseconazole (VT-1161) is an orally active anti-fungal agent. Oteseconazole displays no obvious effect on human CYP51. It also potently binds to and inhibits Candida albicans CYP51 (Kd, <39 nM).
T8536 Filastatin Antifungal
Filastatin is a long-lasting inhibitor of Candida albicans filamentation, and has potent antifungal effect.
TN1651 Furanodiene Apoptosis , PARP , Reactive Oxygen Species , Caspase , CDK , P-gp
Furanodiene has anti-inflammatory and antioxidant activities, it is active against gram-positive bacteria and Candida albicans.
T77686 1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone Antifungal
1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone has broad-spectrum antifungal activity with inhibitory effects on Candida albicans, Aspergillus niger, Pseudomonas aeruginosa and Staphylococcus aureus.
T1678 Nystatin Stamycin,Fungicidin,Nystavescent Apoptosis , Antibiotic , Antifungal
Nystatin (Fungicidin) is a topical and oral antifungal agent with activity against many species of yeast and candida albicans, which is used largely to treat skin and oropharyngeal candidiasis.
T0011 2-Phenylethanol Phenethyl alcohol,2-Phenylethyl alcohol,Benzyl carbinol,Phenylethanol,Benzeneethanol Others , Virus Protease , Antibacterial , Antibiotic
2-Phenylethanol (Phenylethanol) is an antimicrobial, antiseptic, and disinfectant. It is used also as an aromatic essence and preservative in pharmaceutics and perfumery.
T25718 Lichesterol
Lichesterol is extracted from polyene antibiotic-resistant Candida albicans.
T13787 N-563 Others
N-563 promotes resistance to Candida albicans infection in mice
T35297 ZD 0870 D 0870,D0870,ZD0870
ZD 0870, used to treat infections caused by fluconazole-resistant candida albicans.
T28596 RO-09-4609 RO 09-4609,RO09-4609,RO 094609,RO-094609
RO-09-4609 is a potent and selective inhibitor of Candida albicans N-myristoyltransferase (CaNmt).
T61502 Antifungal agent 32
Antifungal agent 32 (compound 1a) is a highly effective antifungal compound. It displays strong inhibitory activity against Candida albicans filamentation and biofilm formation, as well as inhibiting the morphological sw...
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