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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1388 | Fluconazole | UK-49858 | Antibiotic , Antifection , Antifungal |
Fluconazole (UK-49858) is a triazole antifungal agent that is used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS. | |||
T38240 | 2,6-Dichlorodiphenylamine | Antibacterial | |
2,6-Dichlorodiphenylamine is an analogue of Diclofenac Sodium and has anti-Candida albicans activity. Diclofenac Sodium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1... | |||
T27617 | Inz-1 | P450 | |
Inz-1 is an effective and fungal-selective inhibitor of mitochondrial cytochrome bc1 with IC50s of 8.092 and 45.320 μM for yeast and human. Inz-1 reverses Fluconazole or other triazole antifungals’ resistance in the path... | |||
T21678 | 3MB-PP1 | PLK | |
3MB-PP1 is a bulky purine analog and a Polo-like kinase 1 (Plk1) inhibitor. In cells expressing analog-sensitive Plk1 alleles, 3MB-PP1 blocks mitotic progression and cell division arise by targeting Plk1. 3MB-PP1 specifi... | |||
T19717 | Cyclo-L-Trp-L-Trp | Antifungal | |
Cyclo-L-Trp-L-Trp is a broad-spectrum antifungal. It also induces a high degree of acetylation of histones. | |||
T14046 | Anandamide | (5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide | Cannabinoid Receptor , Endogenous Metabolite |
Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55) in the central nervous sy... | |||
T17022 | Tebuconazole | P450 , Antifungal | |
Tebuconazole is an agricultural azole fungicide. It can also inhibit CYP51 (IC50s: 0.9 and 1.3 μM for Candida albicans CYP51 and truncated Homo sapiens CYP51, respectively). | |||
T9602 | Monocaprin | Anti-infection , Antibacterial | |
Monocaprin is a 1-monoglyceride of capric acid that has antimicrobial activity against enveloped viruses, certain bacteria, and the yeast Candida albicans. | |||
T7029 | Pseudolaric Acid C | Antifungal | |
Pseudolaric Acid C has weak antifungal activity against Candida albicans. | |||
T16412 | Oteseconazole | VT-1161 | P450 , Antifungal |
Oteseconazole (VT-1161) is an orally active anti-fungal agent. Oteseconazole displays no obvious effect on human CYP51. It also potently binds to and inhibits Candida albicans CYP51 (Kd, <39 nM). | |||
T8536 | Filastatin | Antifungal | |
Filastatin is a long-lasting inhibitor of Candida albicans filamentation, and has potent antifungal effect. | |||
TN1651 | Furanodiene | Apoptosis , PARP , Reactive Oxygen Species , Caspase , CDK , P-gp | |
Furanodiene has anti-inflammatory and antioxidant activities, it is active against gram-positive bacteria and Candida albicans. | |||
T77686 | 1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone | Antifungal | |
1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone has broad-spectrum antifungal activity with inhibitory effects on Candida albicans, Aspergillus niger, Pseudomonas aeruginosa and Staphylococcus aureus. | |||
T1678 | Nystatin | Stamycin,Fungicidin,Nystavescent | Apoptosis , Antibiotic , Antifungal |
Nystatin (Fungicidin) is a topical and oral antifungal agent with activity against many species of yeast and candida albicans, which is used largely to treat skin and oropharyngeal candidiasis. | |||
T0011 | 2-Phenylethanol | Phenethyl alcohol,2-Phenylethyl alcohol,Benzyl carbinol,Phenylethanol,Benzeneethanol | Others , Virus Protease , Antibacterial , Antibiotic |
2-Phenylethanol (Phenylethanol) is an antimicrobial, antiseptic, and disinfectant. It is used also as an aromatic essence and preservative in pharmaceutics and perfumery. | |||
T25718 | Lichesterol | ||
Lichesterol is extracted from polyene antibiotic-resistant Candida albicans. | |||
T13787 | N-563 | Others | |
N-563 promotes resistance to Candida albicans infection in mice | |||
T35297 | ZD 0870 | D 0870,D0870,ZD0870 | |
ZD 0870, used to treat infections caused by fluconazole-resistant candida albicans. | |||
T28596 | RO-09-4609 | RO 09-4609,RO09-4609,RO 094609,RO-094609 | |
RO-09-4609 is a potent and selective inhibitor of Candida albicans N-myristoyltransferase (CaNmt). | |||
T61502 | Antifungal agent 32 | ||
Antifungal agent 32 (compound 1a) is a highly effective antifungal compound. It displays strong inhibitory activity against Candida albicans filamentation and biofilm formation, as well as inhibiting the morphological sw... |